Even so, the analysis links oxidative stress to an integral metabolic pathway activated by ATM that integrates damage response pathways with energy signaling, protein synthesis and cell survival.. ATM tumor-suppressor also recognizes damage caused by ROS and orders autophagy DNA damage sensor also responds to oxidative harm outside the nucleus ATM, a protein that reacts to DNA damage by ordering repairs or the suicide of the defective cell, has an identical, previously unknown function in response to oxidative harm outside of the nucleus, researchers statement this week in the online edition of the Proceedings of the National Academy of Sciences.Fruits will be the most common substances of such cures. 4. Learn the causes. It may be hormonal, unhygienic procedures, allergies and also something far worse. Sometimes, acne may not be acne in all but a manifestation of some other condition. Always consult with a doctor if you feel that your pimples are more than they appear. The consequences of careless choices 1. Allergic reaction. Always take note of the medicines you are using. They might have the potential of being harmful when coupled with other drugs. At the same time, don’t just purchase anything off the shelf or make use of what your friend is definitely using, it could work for her or him, but might be harmful to you. 2. Extra costs. If you simply buy a pimple cure without consulting your physician and it didn’t function, that’s money already wasted.