All rights reserved. Neither of these parties endorse or suggest any commercial products, services, or equipment.. ART resistance increasing in sub-Saharan Africa By MedWire Reporters The prevalence of antiretroviral drug resistance is on the rise in sub-Saharan Africa, a rise driven by level of resistance to non-nucleoside reverse transcriptase inhibitors in east and southern Africa, study shows. ‘The findings are of concern and pull attention to the necessity for improved surveillance and drug-resistance prevention initiatives by national HIV programmes,’ compose Silvia Bertagnolio and co-workers in TheLancet. At the end of 2011, more than 8 million people infected with HIV in low – and middle-income countries had been treated with antiretroviral therapy .Changes from baseline to week 12 in the IRLS score were analyzed with a linear combined model and the use of a spatial-power covariance structure. Augmentation rates were analyzed through a stratified log-rank check. The noninferiority of pregabalin with respect to each dose of pramipexole was assessed based on 95 percent confidence intervals for the difference between pregabalin and pramipexole with the use of least-squares means produced from a mixed-effects model; the noninferiority margin was set at 3 points for the IRLS rating. If noninferiority could be declared, a check of superiority was performed, with superiority declared if the higher limit of the confidence interval for the change from baseline in the IRLS score was less than 0.