April 1 in the journal Obstetrics & Genecology The UAB results are published. One alarming trend noted in the study is how often transvaginal ultrasound resulted in a high rate of unnecessary removal of the ovaries, which means no cancers was detected in these organs post-surgery. ‘This data suggests that we are in need of an improved screening tool. We need a test that’s more sensitive and even more specific therefore we find the cancer earlier and we catch the biological markers that give us stronger clues,’ Partridge said. The scholarly study was area of the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial and included a lot more than 72,000 ladies aged 55 to 74. The PLCO outcomes coincide with a British research published March 10 online in The Lancet Oncology that discovered combo screening for ovarian cancer was extremely successful in finding early stage cancers.This is an area which is much under-researched still. A few studies show an impact on DNA mutations which can explain an increased rate of miscarriage, pregnancy loss and birth defect. Advanced paternal age has also been associated with long-term disorders in offspring. But the available evidence is limited. Our results suggest that, up to the age of 45, there is little aftereffect of male age on treatment final result, but sperm donors are a selected human population based on good sperm quality. Our research shows that we are good at choosing the right sperm donors with the right sperm quality – and that's why zero difference was found by us in live birth rate despite the increasing age group of sperm donors.